OsteoThera™ Plus Ipriflavone

Added benefits for bone density†


Benefits and Features

Designed to strengthen the skeletal system and enhance calcium absorption and its incorporation into the bone.† Studies with ipriflavone show it can enhance bone formation and inhibit bone breakdown. It is added to this formula for patients at the highest risk of osteoporosis who are under regular clinical supervision.

Detail Overview

Broad-spectrum healthy bone support from a unique combination of vitamins, minerals, and ipriflavone, an isoflavone derivative that has been clinically shown to support healthy bone maintenance.†

Serving Size 2 Tablets
Amount Per 2 Tablets % Daily Value
Vitamin D3 (as cholecalciferol) 5 mcg 25%
Vitamin K (50% as vitamin K1 phytonadione, 25% as vitamin K2 menaquinone-4, and 25% as vitamin K2 menaquinone-7) 200 mcg 167%
Calcium (as calcium citrate-malate complex) 250 mg 19%
Magnesium (as TRAACS® magnesium bisglycinate chelate, magnesium oxide) 100 mg 24%
Boron (as boron aspartate-citrate complex) 0.5 mg *
Ipriflavone 300 mg *
* Daily value not established

Other Ingredients:

Croscarmellose sodium, cellulose, stearic acid, acacia fiber(Acacia seyal)(bark exudate gum), silicon dioxide, magnesium stearate, cellulose coating, and zinc oxide.

Albion® and TRAACS® are registered trademarks of Albion® Laboratories, Inc.

Suggested Use

2 tablets, 2 times daily with food or as directed by a healthcare professional.

Allergy Statement

Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, and soybeans. Contains no artificial colors, flavors, or preservatives.


If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN. 

California Residents

WARNING: This product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to P65warnings.ca.gov/food

OsteoThera™ Plus Ipriflavone is a vitamin and mineral supplement formulated to support bone health with a more comprehensive formula than calcium alone. Easy-to-absorb calcium citrate-malate is combined with other minerals important for bone health, including magnesium and boron. Vitamins D and K are included to further assist calcium utilization and promote normal bone formation. Ipriflavone, an isoflavone-derived compound, provides additional benefits for bone density.

Ipriflavone is a derivative of naturally occurring isoflavones found in soy. Numerous published clinical trials have demonstrated the efficacy of this flavonoid-like compound in supporting healthy bone mineral density and metabolism. OsteoThera™ Plus Ipriflavone provides 300 mg of Ipriflavone in each serving, the same amount used in clinical studies.

Calcium citrate-malate is significantly more absorbable compared to other forms of calcium, such as calcium carbonate. About 40% more calcium is absorbed from calcium citrate-malate compared to calcium carbonate or milk. Calcium citrate-malate is also well-tolerated. It does not produce intestinal discomfort, constipation, or gas like some forms of calcium.

Proper calcium utilization is crucial to maintain and support normal bone density. Increasing age, sex, race, diet choices, and exercise frequency are all factors that can negatively affect bone health. Magnesium and boron are also necessary for healthy bones. Magnesium supports bone strength and remodeling, while boron promotes calcium and magnesium balance. Vitamin D is essential for calcium absorption and supporting healthy bone mineral density. Vitamin K activates proteins used in bone metabolism. The combined actions of these nutrients create a more comprehensive approach to maintaining bone health.

Several different forms of vitamin K exist, with the primary dietary form being vitamin K1, or phylloquinone, found primarily in green vegetables. Another form of vitamin K known as vitamin K2, or menaquinone, is found in animal products such as meat or eggs, as well as in foods such as cheese and natto, a fermented soy product.

While most of the benefits of vitamin K were previously attributed to vitamin K1, recent research has identified important benefits for vitamin K2. For optimal bone health, this product provides vitamin K1 and vitamin K2 as menaquinone-4 (MK-4) and menaquinone-7 (MK-7).

Suggested use for this product is 2 tablets twice daily with food or as directed by a healthcare professional. This dose supplies 500 mg of calcium and 200 mg of magnesium, or 50% of the RDA for each of these minerals.